Journal of Capital Medical University ›› 2003, Vol. 24 ›› Issue (2): 93-96.

• 论著·基础研究 • Previous Articles     Next Articles

Repair of Rats Peripherial Nerve Gap by Tissue Engineering

Li Xiaoguang, Yang Zhaoyang, Zhang Kaifeng, Cai Qing, Lu Qiang, Ji Man, Xu Qunyuan, Liu YanBeijing   

  1. Center for Neural Regeneration and Repairing, Capital University of Medical Sciences
  • Received:2003-01-15 Revised:1900-01-01 Online:2003-04-15 Published:2003-04-15

Abstract: This study was to explore the possibility of repairing rats sciatic nerve's 20 mm gaps with artificial nerve graft added by Scs. The artificial nerve graft was made of chitosan and collagen. From 8 to 12 weeks after the operation, regenerating nerve joined the nerve ends of the gap. There was no rejection or inflammation. The outcomes of morphometric analysis from artificial nerve graft with Scs were superior to that from control group Ⅱand control group Ⅱ Newly artificial nerve graft with Scs can be a good bridge and promote the nerve to regenerate in reparing the Sciatic nerve gap.

Key words: artificial nerve, chitosan, Schwann cell, peripherial nerve regeneration

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