Protecting Effects of Gegensu on Isoprenaline-induced Myocardial Injury in Rats

Journal of Capital Medical University ›› 2003, Vol. 24 ›› Issue (3): 251-253.

• 论著·基础研究 • Previous Articles Next Articles

Protecting Effects of Gegensu on Isoprenaline-induced Myocardial Injury in Rats

Xu Pingxiang¹, Sun Wei², Hei Ailian¹, Duan Chunli¹, Sun Songsan¹

1. Department of Pharmacology, Capital University of Medical Sciences;2. Capital Institute of Pediatrics

Received:2002-07-04 Revised:1900-01-01 Online:2003-07-15 Published:2003-07-15

Abstract

Abstract: Protective effects of Gegensu on acute myocardial injury induced by isoprenaline were studied in rats. The effects of Gegensu on electro cardiogram, serum CPK and myocardial malonialdehyde(MDA) and superoxide dismutase(SOD) were observed. The results showed that Gegensu inhibited the increase of ST period, decreased the level of CPK, reduced myocardial MDA production and protected myocardial SOD activity in the isoprenaline-induced damage of the rat's heart. The results suggests that Gegensu possesses protective effects on ischemic myocardium.

Key words: gegensu, isoprenaline, myocardial injury, superoxide dismutase, lipid peroxides

CLC Number:

R285.5

Xu Pingxiang;Sun Wei;Hei Ailian;Duan Chunli;Sun Songsan. Protecting Effects of Gegensu on Isoprenaline-induced Myocardial Injury in Rats[J]. Journal of Capital Medical University, 2003, 24(3): 251-253.

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Protecting Effects of Gegensu on Isoprenaline-induced Myocardial Injury in Rats

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