Abstract: We analyzed the content of phospho creatine kinase myocardial isoenzyme(CK-MB)in the serum of SARS patients in order to find out acute myocardial damage in earlier SARS period.Methods:1)Altogether 204 patients were divided into7groups by age,and the highest CK-MB level was collected in every patient.The percentage of patients with abnormal CK-MB level were calculated and analyzed statistically.2)The patients then were divided into two groups,namely one group with normal CK-MB level and the other with abnormal level.The percentage of patients with multiple pathological changes in lung lobes was estimated for each group.Results:CK-MB abnormal percentages were:17%in the group aged below20;22%in the group aged between 41～50;26%in the group aged between 51～60.The average CK-MB levels in turn were(23±11),(19±16),(21±15),(20±10),(24±15),(36±26),and(22±11)IU/L.There were 53% patients with pathological changes in many lobes of lung in the abnormal group,and 35% in the normal group.Conclusions:Acute myocardial damage exists in part of SARS patients.The highest percentage of CK-MB abnormal level is in the group aged between 51～60years old.The highest average CK-MB level is in the group aged between 61～70years old.The percentage of patients with multiple pathological changes in lung lobes in the abnormal group is much higher than the normal group.

Key words: SARS, CK-MB, myocardial damage