Abstract:

Objective To investigate the long-term follow up results of patients with duodenal ulcer perforation managed by simple suture and pharmacal management. Methods All discharged patients (77 patients) with perforated duodenal ulcer consecutively operated on with simple closure underwent follow-up in our hospital from January 1991 to December 2000. According to follow-up data, the long-term results of recurrence of ulcer symptoms for these patients with perforated duodenal ulcer operated on with simple closure were determined. Results The rate of symptomatic ulcer recurrence (VisickⅢ～Ⅳ) and Existing rate of ulcer of postoperative patients with endoscopy examination in four to eight weeks were 15.4%(10/65), 17.5%(7/40) respectively, and reoperation rate was 1.5%(1/65). Conclusion The long-term results indicated that it had a good effect to prevent the recurrence of ulcer symptoms that H₂ receptor antagonists and proton pump inhibitors and drugs of anti-helicobacter pylori were used in patients with perforated duodenal ulcer operated on with simple closure.

Key words: duodenal ulcer, perforation, treatment