Abstract:

Objective To assess the different therapies for endometrial carcinoma retrospectively.Methods From 1960 to 2001,867 patients with endometrial carcinoma were treated in our hospital.Their clinical and pathological data were analyzed retrospectively.The patients were divided into three groups according to the different therapeutic methods: half dose preoperative radio-brachytherapy and surgery(HR+group S),surgery(group S),radiotherapy(group R).Results The 5 year survival ratesof HR+group S,group S and group R were 93.7%,90.7% and 57.8% respectively in clinical stageⅠ(570 cases),88.3%,64.3% and 25.1% respectively in clinical stageⅡ(134 cases).No significant differences between HR+group S and group S were observed in clinical stageⅠand Ⅱ cases respectively(P>0.05).Meanwhile,The 5 year survival rates of HR+group S,and group S were significantly higher than that of group R in clinical stageⅠand Ⅱ(P<0.01).Conclusion For patients with the endometrial carcinoma in clinical stageⅠand Ⅱ,combined treatment is better than radiotherapy;No significant differences between operation combined with half dose preoperative radio-brachytherapy and surgery.

Key words: endometrial carcinoma, treatment, prognosis