Journal of Capital Medical University ›› 2005, Vol. 26 ›› Issue (6): 765-768.
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Peng Jiying, Sun Yilin
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Abstract: Parkinson disease is a kind of neurodegenerative disease.The classic pathological finding of Parkinson disease is Lewy body(LB).Certain genic mutation would induce Parkinson disease, such as α-synuclein, Parkin, UCHL1 which are ascertained to be associated to Parkinson disease.These gene mutants damage the ubiquitin-proteasomes system(UPS), the UPSdysfunction would lead to Parkinson disease.This review focuses the relationship between the three gene mutant action and the ubiquitin-proteasome system.
Peng Jiying;Sun Yilin. Progress of Study on Pathogenic Gene Associatedwith Parkinson Disease[J]. Journal of Capital Medical University, 2005, 26(6): 765-768.
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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/
https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2005/V26/I6/765