Abstract: Objective To evaluate the indications,lens styles,removal methods and results of intraocular lens(IOL)explantation or exchange in the authors department from 1st,July,2005 to 30th,April,2008.Methods The retrospective analysis comprised 39 patients(40 eyes).The mean age was 30 years old.40 IOLs were explanted,34 IOLs in posterior chamber and 6 IOLs in anterior chamber.The anterior-road technique of explantation was used.After the IOLoptic was freed from the capsular bag,it was cut into 2 or 3 pieces through a small incision.38 eyes were through clear corneal incision,and 2 eyes were through sclera tunnel incision.Of the 40 eyes,34 eyes were implanted with new intraocular lens in the same operation.One IOL was implanted into anterior chamber,29 IOLs were into posterior chamber,and 4 IOLs were sutured in ciliary sulcus.Results Indications for IOL removal were malposition of the IOL in 22 eyes,uveitis in 9 eyes,postoperative refractive error in 4 eyes,secondary glaucoma in anterior chamber IOL in 2 eyes,endothelial cell loss in anterior chamber IOL in 2 eyes,and opacification of the IOL in 1 eye.The intraocular lens of 40 eyes were explanted successfully.There was no serious postoperative complications happened.The postoperative corrected visual acuity improved after one month in 26 eyes.Conclusion The most frequent indications for IOLexplantation/exchange were IOLmalposition,uveitis and postoperative refractive error.Intraocular lens explantation in time will lead to better outcome.Final visual results have been largely good.Most cases can get better vision by implanting new intraocular lens.

Key words: intraocular lens, explantation