Clinical study of double needle puncture ozone injection combined with coblation in the treatment of discogenic low back pain

doi:10.3969/j.issn.1006-7795.2015.02.021

Abstract

Abstract:

Objective To observe the efficacy and safety of intervertebral disc double needle injection of ozone combined with ablation for the treatment of discogenic low back pain of coblation target through different minimally invasive methods. Methods Totally 120 patients received minimally invasive interventional treatment for lumbar intervertebral disc were randomly divided into 3 groups, Group A received coblation, Group B received double needle injection of ozone, and Group C received both ablation and double needle injection of ozone. Visual analogue scale(VAS), treatment effect, Oswestry disability index(ODI) and complications were evaluated before the treatment, 3 days, 30 days and 90 days after the treatment for all patients. Results The VAS values after treatment in each group significantly decreased, and the difference was statistically significant(P<0.05), and the VAS value reduction and the therapeutic effect of Group C 30 days and 90 days and the ODI of Group C 90 days after the treatment were much more significant than that of Group A and B(P<0.05). No significant complication happened during treatment. Conclusion The therapeutic effect of the combination of double needle injection of ozone and coblation was more obvious and lasted longer.

Key words: discogenic low back pain, coblation, ozone, double needle

CLC Number:

R614.2

Ge Weipeng, Zheng Guanrong, Du Meiqing, Xu Weimin, Wang Dalong, Zhang Haishan, He Mingwei. Clinical study of double needle puncture ozone injection combined with coblation in the treatment of discogenic low back pain[J]. Journal of Capital Medical University, 2015, 36(2): 282-286.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2015.02.021

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2015/V36/I2/282

References

[1] 何明伟,于密生,孙海燕,等.硬膜外前、侧间隙置管持续注药联合臭氧治疗颈椎间盘突出症的疗效分析[J].中国康复医学杂志,2012,27(8):741-743.
[2] 何明伟,张文祥,倪家骧,等.经皮靶点射频加双针穿刺穿通式臭氧注射治疗腰椎间盘突出症的临床研究[J].中国康复医学杂志,2012,27(4):348-350.
[3] Macnab I. Negative disc exploration. An analysis of the causes of nerve-root involvement in sixty-eight patients[J]. J Bone Joint Surg Am, 1971,53(5):891-903.
[4] Brisby H, Olmarker K, Larsson K, et al. Proinflammatory cytokines in cerebrospinal fluid and serum in patients with disc herniation and sciatica[J]. Eur Spine J, 2002,11(1):62-66.
[5] 王君,杨艳梅,韩悦,等.C型臂引导下等离子髓核低温消融术联合臭氧治疗包容型颈椎间盘突出症的对比观察[J].中国疼痛医学杂志,2012,18(3):152-154.
[6] Ozawa K, Atsuta Y, Kato T. Chronic effects of the nucleus pulposus applied to nerve roots on ectopic firing and conduction velocity[J]. Spine(Phila Pa 1976), 2001,26(24):2661-2665.
[7] Takebayashi T, Cavanaugh J M, Cuneyt Ozaktay A, et al. Effect of nucleus pulposus on the neural activity of dorsal root ganglion[J]. Spine(Phila Pa 1976), 2001,26(8):940-945.
[8] 陈长青,陈蕊,伦保国,等.经后路椎间盘镜下置入腰椎间融合器治疗腰椎间盘突出症临床观察[J].解放军医药杂志,2013,25(2):21-23.
[9] 成杰,陈博文,宋云华,等.经皮激光椎间盘减压术术后患者的健康指导[J].中国煤炭工业医学杂志,2012,15(12):2074-2075.
[10] Chen Y C, Lee S H, Saenz Y, et al. Histologic findings of disc, end plate and neural elements after coblation of nucleus pulposus:an experimental nucleoplasty study[J]. Spine J, 2003,3(6):466-470.
[11] Sinan T, Sheikh M, Buric J, et al. Percutaneous coblation nucleoplasty in patients with contained lumbar disc prolapse:1 year follow-up in a prospective case series[J]. Acta Neurochir Suppl, 2011,108:107-112.
[12] 赵正琦,张素珍,姜风荣,等.低温等离子射频消融髓核成形术治疗LDH疗效观察[J].山东医药,2009,49(22):45-46.
[13] 王泽茂,牟明威,孙国睿.低温等离子射频消融髓核成形术治疗腰椎间盘突出症的临床效果[J].中国医药导报,2014,11(13):48-50,54.
[14] 闫志刚,王元利.低温等离子射频消融髓核成形术治疗腰椎间盘突出症60例的临床观察[J].颈腰痛杂志,2014,35(1):73-74.
[15] 孙海宁,周银,于秀淳,等.经皮等离子消融髓核成形术治疗腰椎间盘突出症的临床研究[J].微创医学,2007,2(2):95-96.
[16] 燕飞,兰忠煜,白希壮.两种手术方法治疗腰椎间盘突出症的疗效比较[J].中国医科大学学报,2013,42(7):666-667.
[17] Andreula C F, Simonetti L, De Santis F, et al. Minimally invasive oxygen-ozone therapy for lumbar disk herniation[J]. AJNR Am J Neuroradiol, 2003,24(5):996-1000.
[18] Steppan J, Meaders T, Muto M, et al. A metaanalysis of the effectiveness and safety of ozone treatments for herniated lumbar discs[J]. J Vasc Interv Radiol, 2010,21(4):534-548.