Journal of Capital Medical University ›› 2020, Vol. 41 ›› Issue (2): 257-260.doi: 10.3969/j.issn.1006-7795.2020.02.019

• Clinical Research • Previous Articles     Next Articles

Clinical presentations and CT features of COVID-19

Li Xiaohu1, Qiu Xiaohui2, Zhang Jinping3, Zeng Xiaosong4, Xu Qizhong5, Huang Guoquan6, He Kewu7, Ma Yichuan8, Wu Zongshan9, Shi Hengfeng10, Yuan Yushan11, Liu Bin1, Yu Yongqiang1   

  1. 1. Department of Radiology, the First Affiliated Hospital of Anhui Medical University, Anhui Province Clinical Image Quality Control Center, Hefei 230022, China;
    2. Department of Radiology, The People's Hospital of Bozhou, Bozhou 236800, Anhui Province, China;
    3. Department of Radiology, Tongling People's Hospital, Tongling 244000, Anhui Province, China;
    4. Department of Radiology, Suzhou Hospital Affiliated to Anhui Medical University, Suzhou 234000, Anhui Province, China;
    5. Department of Radiology, Chaohu Hospital of Anhui Medical University, Chaohu 238001, Anhui Province, China;
    6. Department of Radiology, The Second People's Hospital of Wuhu, Wuhu 241001, Anhui Province, China;
    7. Department of Radiology, The First People's Hospital of Hefei, Hefei 230001, China;
    8. Department of Radiology, the First Affiliated Hospital of Bengbu Medical college, Bengbu 233004, Anhui Province, China;
    9. Department of Radiology, The Lu'an affiliated hospital, Anhui Medical University, Lu'an 237005, Anhui Province, China;
    10. Department of Radiology, Anqing Municipal Hospital, Anqing 246003, Anhui Province, China;
    11. Department of Radiology, Fu Yang People's Hospital, Fuyang 236000, Anhui Province, China
  • Received:2020-02-28 Online:2020-04-21 Published:2020-04-16
  • Supported by:
    This study was supported by Anhui Natural Science Emergency Foundation （20200410702003）， Anhui Province Programs for Science and Technology Development（201904a07020060），Intercollegiate Key Projects of Nature Science of Anhui Province （KJ2018A0197）. #共同第一作者

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Abstract: Objective To investigate the thoracic computed tomography(CT) and clinical manifestations of COVID-19. Methods Chest CT and clinical data of confirmed 26 patients COVID-19 were retrospectively analyzed. Results In terms of clinical manifestations, fever and cough were main manifestations with 26 patients (100%) and 21 patients (80.8%) respectively, which could be accompanied by muscle soreness, shortness of breath, diarrhea or vomiting. Laboratory examination showed that 15 patients (57.7%) was normal in white blood cell (WBC),4 patients (15.4%) increased and 7 patients (26.9%) decreased. Lymphocytopenia occurred in 10 patients (38.5%). C-reactive protein(CRP) was elevated in 15 patients (57.7%). In terms of CT features, lesions were found in the lung high resolution computerized tomography(HRCT) of 26 all patients, with unilateral lung distribution in 6 patients (23.1%), mainly subpleural distribution;bilateral lung distribution in 20 patients (76.9%). All lobes and segments of both lungs were involved in 6 patients (23.1%). In focal cases, the involvement of the right lower lobe was the most common with 10 patients (38.5%). One or more of the following signs could be seen in 26 patients with COVID-19:ground -glass opacity(GGO) in 16 patients (61.5%), mainly subpleural distribution;GGO combined with focal consolidation in 6 patients (23.1%); small patchy blur with increased density in 10 patients (38.5%); large patchy consolidation in 7 patients (26.9%); fibrosis, grid shadow in 8 patients (30.8%); bronchovascular bundle thickening and vascular perforator sign were seen in 5 patients (19.2%); air bronchial signs were seen in 4 patients (15.4%); a small amount of pleural effusion was seen in 1 patient (3.8%). Enlargement of mediastinal and hilar lymph nodes was absent. Conclusion Chest CT of COVID-19 shows GGO distributed in multiple sites, periphery, subpleural and lower lobes, which may be accompanied by consolidation. Pleural effusion and enlarged lymph nodes are rare. Chest CT provides an important basis for early prevention and control, early diagnosis and treatment of the disease.

Key words: coronavirus, COVID-19, computed tomography (CT)

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