Abstract: Objective To analyze the early stage characteristics COVID-19 in Yicheng area in terms of computed tomographic (CT) imaging and clinical features. Methods The data of 66 patients with COVID-19 diagnosed in Yicheng People's Hospital from January 16 to February 9, 2020 were analyzed retrospectively. All patients underwent laboratory examination and chest CT examination at the first visit. The basic information of patients, laboratory examination results, and chest CT image characteristics of patients in the early stage of onset were analyzed and summarized. Results Totally 66 COVID-19 patients were 21-71 years. Based on the degree of illness on admission, they were divided into mild type (n=4), common type (n=51), severe type (n=6), and critical type (n=5). The main symptoms were fever, cough, and fatigue. Laboratory examination showed that lymphocyte percentage decreased, C-reactive protein increased, erythrocyte sedimentation rate (ESR) increased, eosinophils (EOS) decreased, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) increased, blood urea nitrogen (BUN) and creatinine (CREA) decreased, and albumin (ALB) decreased. Brain natriuretic peptide (BNP), fibrin (FIB), and D-Dimer (D-D) increased significantly in severe and critical patients. The chest CT results showed no obvious abnormality in the chest CT imaging examination of mild patients. 15 cases (29.41%) had single lesion and 36 cases (70.59%) had multiple lesions in common type cases. 1 case (16.67%) had single lesion and 5 cases (83.33%) had multiple lesions in severe cases. The main manifestations of chest CT images of common type, severe type and critical type patients were patchy high-density shadow and ground glass shadow. Conclusion The laboratory indexes of COVID-19 patients in Yicheng area had obvious changes. In the early stage of the disease, the main CT manifestations were patchy high-density shadow and ground glass shadow. The location of the lesions was double lung, subpleural and lung field zone. This result has a strong reference value for the early diagnosis and treatment of viral infection.

Key words: novel coronavirus pneumonia, a retrospective study, typing