Abstract: Objective To investigate the anesthesia and perioperative management in laparoscopic adrenalectomy for pheochromocytoma in comparison with traditional adrenalectomy. Methods Ten patients receiving laparoscopic adrenalectomy for pheochromocytoma under general anesthesia were allocated into laparscope group(group L), and another 10 patients receiving traditional adrenalectomy were allocated into control group(group C). Hemodynamic changes, using of vasoactive drugs, fluid infusion, duration of surgery and hospitalization days in each group were compared. Results In both groups, comparing with those at the time point of intubation, mean arterial blood pressure(MAP) increased 20 minutes after artificial pneumoperitoneum and during the period of severing the tumor(P<0.05 ); MAP decreased significantly after excision of the tumor(P<0.05) as compared with those at intubation; heart rate(HR) also increased during the period of severing the tumor(P<0.05). There was no difference between two groups in MAP and HR at each time point. There was no difference between two groups in the usage of vasoactive drugs; as well as no differences in fluid infusion and duration of surgery in the two groups. Hospitalization days were fewer in group L than in group C, but there was no difference statistically. Conclusion There is similar risks in anesthesia in laparoscopic adrenalectomy for pheochromocytoma and traditional adrenalectomy. However, patients undergoing laparoscopic surgical procedure recover faster as compared with that of open surgery.

Key words: laparoscopic, pheochromacytoma, anesthesia, hemodynamic changes