Journal of Capital Medical University ›› 2015, Vol. 36 ›› Issue (4): 640-644.doi: 10.3969/j.issn.1006-7795.2015.04.025

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Resting state functional MRI, DTI and PWI in the Alzheimer's disease

Wang Zhiqun1, Li Kuncheng2,3,4   

  1. 1. Department of Radiology, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China;
    2. Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China;
    3. Key Laboratory for Neurodegenerative Disorders of the Ministry of Education, Capital Medical University, Beijing 100053, China;
    4. Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing 100053, China
  • Received:2014-01-13 Online:2015-08-21 Published:2015-07-17
  • Supported by:

    This study was supported by National Natural Science Foundation of China(81471649, 81370037), Natural Science Foundation of Beijing(7153166).

Abstract:

Alzheimer's disease(AD) is characterized as cognitive and memory decline. Mild cognitive impairment(MCI) is the early stage of AD. The pathophysiology of AD is not very clear. In the present article, we reviewed the previous neuroimaging study of AD. By using the new MRI techniques including resting state functional MRI(fMRI), diffusion tensor imaging(DTI) and perfusion weighted imaging(PWI), we can acquire deep understanding of the pathophysiology of AD from the prospect of function, structure and perfusion.

Key words: Alzheimer's disease, mild cognitive impairment, functional MRI, diffusion tensor imaging, perfusion weighted imaging

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