Journal of Capital Medical University ›› 2006, Vol. 27 ›› Issue (2): 271-274.
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Peng Jiying, Sun Yilin
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Abstract: Parkinson disease is a kind of neurodegenerative disease.The classic pathological finding of Parkinson disease is Lewy body(LB).Certain genic mutation would induce Parkinson disease,such as α-synuclein,Parkin,UCHL1 which are ascertained to be associated to Parkinson disease.These gene mutants damage the ubiquitin-proteasomes system(UPS),the UPS dysfunction would lead to Parkinson disease.This review discasses the relation between the three gene mutant ation and the ubiquitin-proteasomes system.
Peng Jiying;Sun Yilin. The Study in Pathogenic Gene Associate with Parkinsonis Disease[J]. Journal of Capital Medical University, 2006, 27(2): 271-274.
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https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2006/V27/I2/271