Abstract: Objective To design an experimental system, which can simulate the pupil-blocking phenomena and passive deformation of iris tissue without destroying orbicular structure and activity of iris and to measure passive deformation of rabbit iris when difference between the pressure of anterior chamber and the pressure of posterior chamber changed. Methods The binocular stereo system, which was designed and improved upon the primary experimental device, can obtain continuous pressure data and corresponding 2D image of iris from two cameras in the course of load-pressure. The authors computed 3D coordinate of iris related to the difference of pressure based on stereo vision then dealt with the coordinate of Z axes, which was the height of passive deformation of iris, and obtained the curve of relation between the height of passive deformation of iris and the difference in pressure. Results The 3D data of iris during load-pressure was increased from 0 to 600 Pa. Sever curves of iris were 50 Pa, 100 Pa, 200 Pa, 300 Pa, 400 Pa, 500 Pa and 600 Pa. Conclusion Passive deformation occurred in rabbit iris tissue when load-pressure was increased.

Key words: pupil-blocking, passive iris deformation, stereo vision, primary angle closure glaucoma