Journal of Capital Medical University ›› 2017, Vol. 38 ›› Issue (3): 381-385.doi: 10.3969/j.issn.1006-7795.2017.03.011

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Effects of Songlingxuemaikang (SLXMK) on blood pressure level and glucolipid metabolism in patients with mild essential hypertension

Sun Xipeng, Ding Cuntao, Zhou Yaqun, Zhu Weiwei, Tan Jing, Li Jing, Hua Qi   

  1. Department of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • Received:2017-01-14 Online:2017-05-21 Published:2017-06-14
  • Supported by:
    This study was supported by Beijing Lab for Cardiovascular Precision Medicine,Beijing,China(PXM2016_014226_000023).

Abstract: Objective To investigated the effects of Songlingxuemaikang (SLXMK) on blood pressure level and glucolipid metabolism in patients with mild essential hypertension. Methods We enrolled 90 patients with mild essential hypertension in Xuanwu Hospital from January 2016 to December 2016. To evaluate the effects of SLXMK, the 90 patients were randomly assigned at a 2:1 ratio into 2 groups:the SLXMK group (500 mg per capsule, 4 500 mg/d, n=60) and the losartan potassium group (50 mg per table, 50 mg/d, n=30). The total study period was 12 weeks, and all patients maintained a stable diet and life-style during this period.Results After 12 weeks treatment, there was no interaction effect between the treatment methods of blood pressure level and glycometabolism parameters and duration (P>0.05). In the SLXMK group, plasma lipid levels significantly improved and there was interaction effect between the treatment methods and duration (P<0.05).Conclusion In conclusion, SLXMK could effectively improve plasma lipid levels in patients with mild essential hypertension.

Key words: Songlingxuemaikang, essential hypertension, plasma lipid

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