Screening results and significance of 9 013 cases of transfusion irregular antibody

doi:10.3969/j.issn.1006-7795.2017.05.023

Abstract

Abstract: Objective To analyze screening results of 9 013 cases of transfusion irregular antibody, and to explore the clinical significance of the irregular antibody screening. Methods Totally 9 013 cases of patients underwent blood transfusion from July 2013 to August 2016 in Beijing Chaoyang Hospital, Capital Medical University were analyzed retrospectively. The irregular antibody screening and identification were applied with micro-column gel technology. The positive rate of irregular antibody, distribution and irregular antibody positive rate in the different departments were analyzed statistically. In addition, the influence of gender and blood transfusion/history of pregnancy on irregular antibody positive rate. Results The irregular antibody positive rate of 9 013 cases of transfusion of blood specimen was 0.63% (57/9 013), in which mainly for the Rh, was accounted for 42.11% (24/57); Second of MNS type, which was accounting for 24.56% (14/57); Other type and proportion were Lewis system (10.53%), Kidd system (8.77%), P (5.26%) and other (8.77%), respectively. The irregular antibody rate in surgery department was 1.06% (14/1 321), significantly higher than other department 0.59% (43/7 692), with significant difference (P<0.05). The irregular antibody positive rate of women transfusion was 0.94% (30/3 187), which was significantly higher than the 0.46% of male patients (27/5 826), and the difference was statistically significant (P<0.05). The irregular antibody positive rate of patients with blood transfusion/pregnancy history was 0.85% (34/3 986), which was significantly higher than that with no history of transfusion blood transfusion/pregnancy[0.46% (23/5 027)] (P<0.05). Conclusion The irregular antibody screening before blood transfusion is of great significance for the improvement of blood transfusion safety, which provides suitable for screening patients with positive blood type. It can reduce clinical immune hemolysis events in order to increase the effectiveness of blood transfusion.

Key words: blood transfusion, irregular antibody, screening

CLC Number:

R457

Wu Di. Screening results and significance of 9 013 cases of transfusion irregular antibody[J]. Journal of Capital Medical University, 2017, 38(5): 753-757.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2017.05.023

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2017/V38/I5/753

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