Journal of Capital Medical University ›› 2021, Vol. 42 ›› Issue (4): 601-608.doi: 10.3969/j.issn.1006-7795.2021.04.015

• Clinical Research • Previous Articles     Next Articles

Analysis of related risk factors of colorectal adenomatous polyps

Xing Jie1, Ren Junyao1, Zhang Qian1, Sun Xiujing1*, Yue Bing2, Zhang Yijun3, Li Rongxue1, Zhu Shengtao1, Li Peng1, Zhang Shutian1   

  1. 1. Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing 100050, China;
    2. Department of Pathology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing 100050, China;
    3. Department of Infectious, The Affiliated Hospital of Guizhou Medical University, Guiyang 550025, China
  • Received:2021-02-08 Online:2021-08-21 Published:2021-07-29
  • Contact: * E-mail:sunxiujing@ccmu.edu.cn
  • Supported by:
    National Natural Science Foundation of China (82070550), The Digestive Medical Coordinated Development Center of Beijing Hospitals Authority (XXZ01, XXZ02).

Abstract: Objective To investigate the risk factors of colorectal adenoma incidence. Methods Data of 662 patients with polypoid lesions admitted at Beijing Friendship Hospital from March 2013 to November 2014 were retrospectively collected, including the basic information such as age, gender, body mass index(BMI), family history, past medical history etc. Totally 140 cases of the patients were pathologically diagnosed as colorectal adenoma and 522 subjects of the patients were enrolled as control group. Combined with the collected data, the risk factors had been analyzed. Results The student t test showed that the age was the risk factor of colorectal adenoma (P<0.05). The chi-square test or Fisher exact test showed that the gender, smoking, drinking and polyp-growing history were correlative factors of colorectal adenoma(P<0.05). The multivariate analysis suggested the age (P<0.001), smoking (P=0.021) and drinking (P=0.022) were independent risk factors of colorectal adenoma. Conclusion The age, cigarette smoking, alcohol intake are independent risk factors of colorectal adenoma. Therefore, we should consider the relevant risk factors of the patients and screen high-risk groups to improve the detection rate of adenoma.

Key words: colorectal adenoma, detection rate, risk factors, screening

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