Predictive value of haptoglobin on renal dysfunction in patients with early diabetic kidney disease

doi:10.3969/j.issn.1006-7795.2019.01.010

Abstract

Abstract: Diabetic kidney disease is an important complication that occurs in some diabetes patients, and it is a leading cause of end-stage renal disease.Biomarkers predicting the deterioration of renal function are important in clinical settings.Microalbuminuria, creatinine and urea nitrogen are widely used as markers to predict renal function decline, but the predictive value of these markers for kidney damage are limited.It is necessary to further search the indicators of diabetic kidney disease for early diagnosis. Several studies suggested that urine haptoglobin is a novel biomarker for predicting kidney damage in patients with diabetes.This article reviews the clinical significance and related mechanisms of the predictive value of haptoglobin on renal dysfunction in patients with early diabetic kidney disease.

Key words: haptoglobin, diabetic kidney disease, predict

CLC Number:

R692
R58

Zheng Xiaomin, Yang Fangyuan, Liu Cuiping, Yang Jinkui. Predictive value of haptoglobin on renal dysfunction in patients with early diabetic kidney disease[J]. Journal of Capital Medical University, 2019, 40(1): 53-58.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2019.01.010

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2019/V40/I1/53

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