Clinical characteristics and risk factors of obstructive sleep apnea syndrome in patients with type 2 diabetes mellitus

doi:10.3969/j.issn.1006-7795.2020.01.007

Abstract

Abstract: Objective To study the clinical characteristics and risk factors of obstructive sleep apnea syndrome(OSAHS) in patients with type 2 diabetes mellitus(T2DM), and analysis the correlation. Methods Patients were divided into OSAHS group(225 cases) and non-OSAHS group (76 cases) in Beijing Anzhen Hospital, Capital Medical University from 2012 to 2019.Height, body weight, body mass index (BMI), waist circumference(WC), systolic blood pressure(SBP) and diastolic blood pressure (DBP) were measured in all cases. Fasting plasma glucose(FPG), hemoglobin A1c (HbA1c), blood lipid, uric acid(UA), liver and kidney function indexes were tested. Result Compared with the non-OSAHS group, WC, BMI, UA, and HbA1c levels were significantly increased (P<0.05 or 0.01). Compared with the non-OSAHS group, the prevalence of hypertension and coronary heart disease was significantly increased (P<0.05), and high density lipoprotein cholesterol(HDL-C) was significantly decreased (P<0.01). Multivariate Logistic analysis was performed with OSAHS in T2DM patients as the dependent variable. The results showed that the history of coronary heart disease, WC, UA, HDL-C and HbA1c were the risk factors for T2DM combined with OSAHS. Conclusions T2DM patients have a history of coronary heart disease, increased waist circumference, high uric acid level, low HDL-C level and high HbA1c, which increase the risk of OSAHS.

Key words: type 2 diabetes mellitus, obstructive sleep apnea hypopnea syndrome, polysomnography, coronary heart disease

CLC Number:

R587

Wei Jiajie, Jiao Jie, Zhou Yingsheng. Clinical characteristics and risk factors of obstructive sleep apnea syndrome in patients with type 2 diabetes mellitus[J]. Journal of Capital Medical University, 2020, 41(1): 35-39.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2020.01.007

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2020/V41/I1/35

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