Efficacy of music therapy combined with bright light therapy on sleep disorders in patients with Alzheimer's disease

doi:10.3969/j.issn.1006-7795.2021.03.005

Abstract

Abstract: Objective To explore the effect of combination therapy with music therapy (MT) and bright light therapy (BLT) on sleep disorders in patients with moderate-severe Alzheimer's disease (AD). Methods A total of 120 patients with moderate or severe AD accompanied with sleep disorders were randomly divided into 4 groups: routine therapy group (control group), MT group, BLT group, and combination therapy group. All patients in the 4 groups received routine treatment. Besides listening to soothing music for 30 minutes before bedtime was supplemented to the MT group, while bright light exposure in the morning for 30 minutes was supplemented to the BLT group; Both MT and BLT were performed in the combination therapy group. The Pittsburgh Sleep Quality Index (PSQI) was evaluated before and after the intervention which lasted for 4 consecutive weeks. Results The baseline characteristics, scores of PSQI and its subscores had no significant difference in the pre-intervention assessment among 4 groups (P>0.05). In the comparison of the difference between pre- and post-intervention, the decrease of the score of sleep medication in the combination therapy group was higher than that in the BLT group, with a statistically significant difference (P<0.05), while in the comparison of the PSQI total score and the scores of other components between the two groups, the difference was not statistically significant (P>0.05). However, the scores of PSQI, sleep quality, sleep latency, sleep efficacy and daytime dysfunction in the combination therapy group and BLT group decreased more significantly than those in the MT group and the control group (P<0.05). The score of PSQI and sleep medication in the MT group decreased significantly compared with the control group, and the differences were both statistically significant (P<0.05). Conclusion The routine treatment supplemented by MT in combination with BLT can effectively improve the overall sleep quality for patients with moderate or severe AD accompanied with sleep disorders, but MT or BLT alone is only effective for certain components of sleep disorders.

Key words: Alzheimer's disease, sleep disorders, music therapy, bright light therapy

CLC Number:

R749.1

Hu Yueqing, Lyu Jihui, Wang Qiang, Ma Zongjuan, Li Wenjie, Mu Haiyan, Li Mo, Gao Wenchao, Jia Dongmei. Efficacy of music therapy combined with bright light therapy on sleep disorders in patients with Alzheimer's disease[J]. Journal of Capital Medical University, 2021, 42(3): 367-372.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2021.03.005

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2021/V42/I3/367

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