Association between serum CXCL16 levels and carotid atherosclerosis in stroke

doi:10.3969/j.issn.1006-7795.2012.02.001

Journal of Capital Medical University ›› 2012, Vol. 33 ›› Issue (2): 139-142.doi: 10.3969/j.issn.1006-7795.2012.02.001

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Association between serum CXCL16 levels and carotid atherosclerosis in stroke

WANG Ke-di¹, LIU Zhi-zhong², WANG Rui-min², KANG Xi-xiong²

1. Department of Clinical Laboratory, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China;2. Department of Clinical Laboratory, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China

Received:2011-11-09 Revised:1900-01-01 Online:2012-04-21 Published:2012-04-21

Abstract

Abstract: Objective To study association between serum CXCL16 levels and carotid atherosclerosis in patients with stroke. Methods A total of 135 cases with acute atherosclerotic stroke were examined using ultrasound to evaluate their carotid atherosclerotic lesions, the patients were then divided into normal(intima-median thickness,IMT) and increased IMT group, without plaque, stable plaque and vulnerable plaque group, 4 groups according to carotid plaque area(CPA) quartiles. Results Serum CXCL16 levels were closely associated with increased IMT, vulnerable plaque and increased CPA, logistic analysis showed that increased serum CXCL16 levels was independent risk factor of increased IMT, vulnerable plaque and increased CPA. Conclusion CXCL16 is an independent risk factor of carotid atherosclerosis in stroke, detection of it may be a new way to find early atherosclerosis.

Key words: chemokine, CXCL16, atherosclerosis, carotid, stroke

CLC Number:

R 743.3

WANG Ke-di;LIU Zhi-zhong;WANG Rui-min;KANG Xi-xiong. Association between serum CXCL16 levels and carotid atherosclerosis in stroke[J]. Journal of Capital Medical University, 2012, 33(2): 139-142.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2012.02.001

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2012/V33/I2/139

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Association between serum CXCL16 levels and carotid atherosclerosis in stroke

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