Journal of Capital Medical University ›› 2022, Vol. 43 ›› Issue (4): 505-520.doi: 10.3969/j.issn.1006-7795.2022.04.001

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Strengthening research on the cerebral venous system improves the diagnosis and treatment of neurological diseases——anatomy, physiology, and clinical overview

Zhou Yifan1, Jiang Huimin1, Wei Huimin2, Gu Yuhang3, Hu Wenbo4, Liu Lu4, Zhou Chen1,4*, Ji Xunming1,5*   

  1. 1. Beijing Institute of Brain Disorders of Capital Medical University, Beijing 100069, China;
    2. Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China;
    3. China-Japan Union Hospital of Jilin University, Changchun 130033, China;
    4. Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China;
    5. Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • Received:2022-05-26 Online:2022-08-21 Published:2022-10-28
  • Contact: *E-mail:chenzhou2013abc@163.com, jixm@ccmu.edu.cn
  • Supported by:
    This study was supported by Project of Beijing Science and Technology(Z181100001918026).

Abstract: The brain is the most metabolically active organ in the human body, and it requires abundant blood supply to maintain complex functional activities. The blood supply of the human brain is divided into the arterial system and the venous system. The cerebral venous system holds 70%-80% of the intracranial blood volume,which plays an important role in ensuring blood perfusion and removing metabolic waste, maintaining the integrity of the blood-brain barrier, regulating intracranial pressure, immune monitoring, and even regulating the meningeal lymphatic function. As a new research field, cerebral venous system has attracted more and more attentions to its pathophysiological role in maintaining cerebral homeostasis and various acute/chronic central nervous system diseases. This review summarizes the anatomical drainage and structural characteristics of cerebral vein system, physiological functions of cerebral vein and its pathological role in central nervous system diseases, aiming to provide references for comprehensively scientific understanding of cerebral vein function and various central nervous system diseases.

Key words: cerebrovascular, cerebral vein, cerebral venous sinus, venous sinus thrombosis, cerebral venous reflux disorder

CLC Number: