Correlation between residual lipoprotein cholesterol and acute myocardial infarction

doi:10.3969/j.issn.1006-7795.2023.05.024

Abstract

Abstract: Objective To investigate the correlation between residual lipoprotein-cholesterol (RLP-C) and acute myocardial infarction (AMI) by analyzing the changes of blood lipid levels in different subgroups of patients with coronary heart disease.Methods Patients with coronary heart disease who were admitted to the Department of Cardiology, Beijing Chaoyang Hospital, Capital Medical University from January 2020 to January 2021 were selected as the study objects. The total of 266 patients with AMI were selected as the case group (AMI group) and 267 patients with non-AMI were selected as the control group (non-AMI). The RLP-C index and atherogenic index of plasma(AIP) were calculated based on the formula. The relationship between RLP-C level and AMI was analyzed by univariate analysis and multiple Logistic regression model.Results The results of univariate analysis showed that the level of RLP-C in AMI group was significantly higher than that in non-AMI group, and the difference was statistically significant (P<0.05). Multivariate Logistic regression showed that after controlling the interference effect of other factors, RLP-C was still an independent risk factor for AMI (P<0.05). Patients with elevated levels of RLP-C had an increased risk of AMI, and among many influencing factors, RLP-C was most closely related to AMI (OR=3.093, 95% CI: 1.658-5.771).Conclusions Serum RLP-C level is associated with AMI, and the risk of AMI increases in patients with elevated RLP-C level.

Key words: acute myocardial infarction, residual lipoprotein cholesterol, blood lipids

CLC Number:

Feng Dan, Li Na, Hou Dongyan. Correlation between residual lipoprotein cholesterol and acute myocardial infarction[J]. Journal of Capital Medical University, 2023, 44(5): 872-876.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2023.05.024

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2023/V44/I5/872

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