Chinese expert consensus on cytoprotection based on reperfusion therapy for acute ischemic stroke

doi:10.3969/j.issn.1006-7795.2026.01.001

Abstract

Abstract: Stroke is a leading cause of mortality and disability worldwide, with approximately 70% of all cases being acute ischemic strokes. Reperfusion therapy (such as intravenous thrombolysis and emergency endovascular treatment) is the first-line treatment for acute ischemic stroke, yet the prognosis remains suboptimal for some patients. In recent years, research on neuroprotection based on reperfusion therapy has made significant progress, with some cytoprotective drugs and therapies showing promising clinical potential. This consensus summarizes recent advances in the field of cytoprotection based on reperfusion therapy and, in combination with the specific clinical and healthcare context of clinical and healthcare China, develops a practical and clinically applicable expert consensus. It aims to provide a scientific basis for cytoprotection research and clinical application in acute ischemic stroke, further optimizing treatment strategies and improving patient outcomes.

Key words: stroke, reperfusion therapy, cytoprotection, combination therapy, prognosis, consensus statement

CLC Number:

R743.3

Stroke Prevention Project, National Health Commission, Stroke Prevention and Control Professional Committee of the Chinese Preventive Medicine Association. Chinese expert consensus on cytoprotection based on reperfusion therapy for acute ischemic stroke[J]. Journal of Capital Medical University, doi: 10.3969/j.issn.1006-7795.2026.01.001.

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Chinese expert consensus on cytoprotection based on reperfusion therapy for acute ischemic stroke

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