Abstract: Objective To observe the efficacy of treatment using intra-articular triamcinolone acetonide and sodium hyaluronic in patients with knee osteoarthritis.Methods 36 patients with knee osteoarthritis were enrolled in this study.All the patients received intra-articular and trigger point injections of triamcinolone acetonide once a week for 2 consecutive weeks then intracavitary injections of sodium hyaluronic for 5 times with one-week intervals and trigger point injections are as before.Lysholm Knee Scale scores were recorded at baseline,at week 1and at months 3.Results The Lysholm Knee Scale scores at week 1 and at months 3 were significantly higher than that at baseline.Conclusion Intra-articular triamcinolone acetonide and sodium hyaluronic provide clinically significant improvement and a long-term beneficial effects in patients with knee osteoarthritis.

Key words: corticosteroid, sodium hyaluronate, osteoarthritis, intra-articular injection