Journal of Capital Medical University ›› 2012, Vol. 33 ›› Issue (5): 689-694.doi: 10.3969/j.issn.1006-7795.2012.05.028

• 诺贝尔奖 • Previous Articles     Next Articles

Cell development backwards:somatic cell nucleus transfer and induced pluripotent stem cells——introduction of Nobel Prize in Physiology or Medicine 2012

WANG Xuan, WANG Xiao-min   

  1. Department of Neurobiology, Capital Medical University; Key Laboratory for Neurodegenerative Disorders of the Ministry of Education; Beijing Institute for Brain Disorders,Beijing 100069, China
  • Received:2012-10-14 Revised:1900-01-01 Online:2012-10-21 Published:2012-10-21

Abstract: The 2012 Nobel Prize in Physiology or Medicine is awarded jointly to Dr. John B. Gurdon from United Kingdom and Dr. Shinya Yamanaka from Japan for their significant discovery that mature cells can be reprogrammed to become pluripotent. Their breakthrough findings have revolutionized the traditional view on the development program of cells or organisms, leading to an exploration on cell fate reversal.

Key words: somatic cell nucleus transfer, induced pluripotent stem cells, development, reprogramming, Nobel Prize in Physiology or Medicine