Abstract: Objective To understand the neuropsychological development of infants at 6 months of age, and to analyze the developmental differences between different genders and related risk factors.Methods The neuropsychological development scale of 0-6 years old children supervised by Capital Institute of Paediatrics was used to measure 1 470 out-patient infants, and the test results were analyzed with developmental quotient assessment. Results A total of 1 470 infants were investigated in this study, including 781 male infants and 689 female infants, with a sex ratio of 1.13∶1 and average monthly age of (6.12±0.24) months. Among them, there were differences in the neuropsychological development of infants of different genders at6 months of age (P<0.05), with statistical significance. At the same time, there were significant differences in fine movement, adaptive ability, and social behavior energy area (P<0.05). The scores of boys were significantly lower than those of girls. Multifactorial logistic analysis showed that low developmental quotient of babies, born gestational age (OR=14.215), the smaller and pregnancy associated with other risk factors babies (OR=4.738), the possibility of delay, the greater the infants with low developmental quotient, gender is a boy (OR=5.061), the smaller the gestational age of birth (OR=80.604) and pregnancy associated with other risk factors (OR=5.673) possibility of slow baby. Conclusion Male infant development quotient is more prominent than that of female infants, showing significant performance in the three functional areas of fine movement, adaptability and social behavior, small gestational age,other high-risk factors associated with pregnancy, and the risk factors of abnormal neuropsychological development in infants aged 6 months.

Key words: infant, neuropsychological development, risk factors, low developmental quotient