Risk factors of adjacent vertebral body fracture secondary to percutaneous vertebral augmentation in elderly patients with osteoporotic vertebral compression fracture

doi:10.3969/j.issn.1006-7795.2021.02.022

Abstract

Abstract: Objective To assess the risk of adjacent vertebral fractures following percutaneous kyphoplasty (PKP) and percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCF) in the elderly, the risk factors for secondary adjacent vertebral fractures were included.Methods The patients with symptomatic single-segment osteoporotic thoracolumbar vertebral compression fractures who were hospitalized in the Orthopedics Department of Beijing Geriatric Hospital from July 2014 to June 2018 were selected as the study subjects, among them, patients with PKP were in the PKP group (189 cases), and patients with PVP were in the PVP group (173 cases). They were followed up for 1 year. The risk of compression fractures of adjacent vertebral bodies after the two surgical methods were compared by statistical analysis.Results Both PKP and PVP significantly reduced visual analogue scale (VAS) scores in 362 patients, and there was no significant difference in the rate of adjacent vertebral fractures between the two groups. Age (OR=1.075,95%CI:1.040-1.112,P<0.001), bone density T value decreased (OR=0.576,95%CI:0.351-0.946,P=0.030), cement leakage(OR=2.284,95%CI:1.200-4.344,P=0.018), postoperative correction of local sagittal Cobb's angle (OR=1.188,95%CI:1.124-1.255,P=0.009)are independent risk factors for adjacent vertebral fractures after OVCF. Conclusion Both PKP and PVP can provide comparable pain relief rates, and there was no difference in the risk of secondary adjacent vertebral fractures between the two procedures. Age, bone mineral density, bone cement leakage (intradiscal leakage) and overcorrection of sagittal Cobb's angle were independent risk factors for secondary adjacent vertebral fractures after OVCF.

Key words: osteoporotic vertebral compression fracture (OVCF), percutaneous kyphoplasty (PKP), percutaneous vertebroplasty (PVP), fracture secondary, risk factors

CLC Number:

R681.5⁺3

Yang Bo, Wang Qinglei, Ma Jianhua, Liang Zhilin, Tang Jie, Zhao Xiaolin, Gao Maolong. Risk factors of adjacent vertebral body fracture secondary to percutaneous vertebral augmentation in elderly patients with osteoporotic vertebral compression fracture[J]. Journal of Capital Medical University, 2021, 42(2): 293-298.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2021.02.022

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2021/V42/I2/293

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