Journal of Capital Medical University ›› 2016, Vol. 37 ›› Issue (2): 109-113.doi: 10.3969/j.issn.1006-7795.2016.02.001

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Application of low concentration contrast media for enhanced CT scan in children with congenital heart disease

Liu Zhimin, Song Lei, Yu Tong, Gao Jun, Jiang Ling, Liu Yong, Peng Yun   

  1. Department of Imaging Center, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China
  • Received:2016-03-01 Online:2016-04-21 Published:2016-04-14
  • Supported by:
    This study was supported by the Department of Maternal and Child Care and Community Health, Ministry of Health.

Abstract: Objective To explore the feasibility of low concentration contrast media 270 mgI/mL iodixanol for enhanced computed tomography (CT) examination of congenital heart disease in children. Methods Sixty patients with congenital heart disease were randomly divided into two groups with 30 cases in each. Groups A and B were scanned with prospective ECG gated scanning scheme. In Group A 270 mgI/mL iodixanol and in group B 320 mgI/mL iodixanol was used. All the cases were scanned on a CT750 HD Discovery (Healthcare GE) with the same parameters of injection of the contrast media. The scanning data were reconstructed by the 30% ASIR, and the two groups of cases were compared with subjective and objective quality evaluation, the dosage of contrast media, and the diagnostic accordance rate. Results All images in two groups met the diagnostic requirements; diagnostic coincidence rate showed no significant difference. Ventricular enhanced degree and contrast to noise ratio of group B were better than those of group A. Comparison of the objective noise and signal to noise ratio and subjective image quality score of the two groups have no significant difference. Conclusion The image of enhanced CT scan with low concentration contrast media can meet the diagnostic requirements for children with congenital heart disease, and can reduce the risk of contrast induced nephropathy.

Key words: heart defect, congenital, tomography, X-ray computed, contrast media, low-concentration contrast media

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