Journal of Capital Medical University ›› 2016, Vol. 37 ›› Issue (5): 631-635.doi: 10.3969/j.issn.1006-7795.2016.05.015

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Association between uric acid and metabolic syndrome among adult people from a 3-A hospital in Beijing

Li Haibin1,2, Tao Lixin1,2, Guo Jin1,2, Liu Xiangtong1,2, Yang Kun1,2, Cao Kai1,2, Wang Chao1,2, Yan Yan3, Guo Xiuhua1,2   

  1. 1. Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China;
    2. Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing 100069, China;
    3. Department of Health Management of Beijing Electric Power Hospital, Beijing 100073, China
  • Received:2015-12-08 Online:2016-10-21 Published:2016-10-19
  • Supported by:
    This study was supported by National Natural Science Foundation of China (81530087,81373099,81502886), Natural Science Foundation of Beijing(7131002), Young Core Personal Project & Beijing Outstanding Talent Training Project(2014000020124G150).

Abstract: Objective To investigate the association between uric acid(UA) 1evels and metabolic syndrome(MS)in the adults in Beijing. Methods A cross-sectional study was carried out in health examination population from a 3-A hospital in 2012 in Beijing. MS was identified by the joint interim statement of Internal Diabetes Federation (IDF), American Heart Association (AHA) and National Heart Lung and Blood Institute (NHLBI) in 2009. All subjects were investigated by using the standardized questionnaires,physical examinations and biochemical measures.UA levels were divided into different groups based on the quartiles.Multivariate Logistic regression was used to explore the relationship between uric acid levels and metabolic syndrome after adjusted age and sex.Results 1 0061 subjects mean aged (43.35±13.18)consisted of 6 089 males and 3 972 females were included in this study. According to quartiles of UA levels, subjects were divided into four groups:Q1(<264.85 μmol/L),Q2(264.85-324.00 μmol/L),Q3(324.01-383.25 μmol/L),Q4(≥383.26 μmol/L).After adjusted for age and sex, compared with Q1, the lower quartile of UA, the odds ratio(OR) of Q2 and corresponding 95% confidence interval (CI) was 1.987 (1.570-2.514), the OR of Q3 was 3.144 (2.470-4.000)and Q4 was 5.821 (4.573-7.410), respectively.Conclusion Uric acid is associated with MS in Beijing adult's population.

Key words: metabolic syndrome, uric acid, multivariate Logistic regression

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