Relationship between mean corpuscular hemoglobin concentration and diabetes mellitus in health examination population in Beijing

doi:10.3969/j.issn.1006-7795.2018.04.018

Abstract

Abstract: Objective To investigate the relationship between mean corpuscular hemoglobin concentration (MCHC) and diabetes mellitus, and to provide evidence for early detection of diabetes mellitus. Methods From the health center of Beijing Xiao Tang Shan Hospital medical population, by using purposive sampling to select fixed unit groups, analysis of indicators MCHC, while controlling for age, body mass index, systolic blood pressure, diastolic blood pressure, low density lipoprotein cholesterol, high density lipoprotein, total cholesterol, triglyceride and other confounding factors. According to the three quartiles of MCHC were divided into four levels, then the crowd divided into two groups according to gender, first the quadratic inference functions (QIF) was used to analyse the relationship between MCHC and diabetes, then the Bayesian network is used to prove the correlation between MCHC and diabetes. Results After screening a total of 6 658 physical examination personnel were selected, including male 4 454, female 2 204. The general condition analysis showed that MCHC levels were different in men and women (P<0.05). According to the QIF analysis, the level of MCHC was positively correlated with the risk of diabetes in both sexes (P<0.05), and the correlation is verified again in the Bayesian network model causal path. Conclusion Mean corpuscular hemoglobin concentration is positively correlated with diabetes mellitus among men and women.

Key words: diabetes mellitus, mean corpuscular hemoglobin concentration, quadratic inference function

CLC Number:

R587.1

Tao Lixin, Mao Qi, Guo Xiuhua, Sun Dianqin, Tian Feifei, Yan Yan. Relationship between mean corpuscular hemoglobin concentration and diabetes mellitus in health examination population in Beijing[J]. Journal of Capital Medical University, 2018, 39(4): 575-580.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2018.04.018

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2018/V39/I4/575

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