Analysis of clinical characteristics and prognosis of the very old and young old patients with mild ischemic stroke

doi:10.3969/j.issn.1006-7795.2022.03.023

Abstract

Abstract: Objective To explore the related factors that affect the prognosis of ischemic stroke in the elders. Methods Selected 247 elder patients with acute ischemic stroke who were hospitalized in the Department of Neurology, Dongcheng First People’s Hospital, Beijing from January 2016 to June 2019. The National Institute of Health Stroke Scale (NIHSS) score ≤3 points, according to age, divided into 113 cases in the elderly group (aged 80 years old and above)and 134 cases in the junior elder group(60-79 years old). The general data, laboratory examination results, Oxford Community Stroke Project (OCSP) classification, etiological classification, risk factors and prognosis of the two groups were compared and analyzed. Results The NIHSS score, diabetes mellitus, history of stroke, history of atrial fibrillation and post stroke pneumonia in elderly patients were significantly higher than those in the middle and low age group (P<0.05). There was no significant difference between the two groups in gender, body mass index (BMI), hypertension, hyperlipidemia, coronary heart disease, valvular heart disease, antiplatelet, anticoagulation, neurological progress, laboratory results, classification and etiology of OCSP (P>0.05). Multivariate Logistic regression analysis showed that the NIHSS score, diabetes mellitus, past stroke history, atrial fibrillation history and post stroke pneumonia were all the influencing factors of 3 months' poor prognosis in elderly patients and middle and low age patients (P<0.05). The factors influencing the prognosis of the two groups were analyzed. The rate of poor prognosis and mortality in the elderly group were higher than those in the middle and low age group (P<0.05). Conclusion NIHSS score, diabetes mellitus, history of stroke, history of atrial fibrillation, and pneumonia after stroke in elderly patients with mild ischemic stroke are higher risk factors for the prognosis of light ischemic stroke in elderly patients.

Key words: elders, mild ischemic stroke, clinical characteristics, prognosis

CLC Number:

R743

Gu Qiang, Yu Xiaojun, Zhang Jin. Analysis of clinical characteristics and prognosis of the very old and young old patients with mild ischemic stroke[J]. Journal of Capital Medical University, 2022, 43(3): 474-479.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2022.03.023

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2022/V43/I3/474

References

[1] 王亚楠, 吴思缈, 刘鸣. 中国脑卒中15年变化趋势和特点[J]. 华西医学, 2021, 36(6): 803-807.
[2] 项丽敏, 赵瑾, 张振芳, 等. 个体化改良康复护理干预对脑卒中偏瘫患者创伤后成长、康复训练依从性及日常生活能力的影响[J]. 护理实践与研究, 2021, 18(24): 3689-3693.
[3] Van Mieghem N M, Wöhrle J, Hildick-Smith D, et al. Use of a repositionable and fully retrievable aortic valve in routine clinical practice: the RESPOND study and RESPOND extension cohort[J]. JACC Cardiovasc Interv, 2019, 12(1): 38-49.
[4] 成云芳, 季燕. 老年轻型缺血性脑卒中患者早期神经功能缺损加重的危险因素分析[J]. 心脑血管病防治, 2019, 19(6): 523-525.
[5] Wang Y L, Zhao X Q, Jiang Y, et al. Prevalence, knowledge, and treatment of transient ischemic attacks in China[J]. Neurology, 2015, 84(23): 2354-2361.
[6] 王伊龙, 赵性泉, 刘新峰, 等. 高危非致残性缺血性脑血管事件诊疗指南[J]. 中国卒中杂志, 2016, 11(6): 481-491.
[7] 邱雪, 薛素芳, 宋海庆. 急性缺血性卒中合并非瓣膜性心房颤动患者出院时口服抗凝药使用情况及其影响因素分析[J]. 中国脑血管病杂志, 2021, 18(11): 753-764.
[8] 中华医学会神经病学分会, 中华医学会神经病学分会脑血管病学组. 中国缺血性脑卒中和短暂性脑缺血发作二级预防指南2014[J]. 中华神经科杂志, 2015, 48(4): 258-273.
[9] Wu L Y, Wang A X, Wang X W, et al. Factors for short-term outcomes in patients with a minor stroke: results from China National Stroke Registry[J]. BMC Neurol, 2015, 15: 253.
[10] 仇建婷, 严江志, 郭婷婷, 等. 老年急性轻型缺血性脑卒中患者的脑梗死模式与病因分析[J]. 中华老年心脑血管病杂志, 2019, 21(11): 1125-1128.
[11] 刘欣, 李小刚, 王红霞, 等. 老年轻型缺血性脑卒中早期进展的临床研究[J]. 中华老年心脑血管病杂志, 2018, 20(4): 401-404.
[12] 马玉苹, 王峥, 陆小伟, 等. 高龄与中低龄老年短暂性脑缺血发作/轻型卒中临床特点比较[J]. 中国神经免疫学和神经病学杂志, 2019, 26(5): 339-342.
[13] Lip G Y H, Clementy N, Pericart L, et al. Stroke and major bleeding risk in elderly patients aged ≥75 years with atrial fibrillation: the Loire valley atrial fibrillation project[J]. Stroke, 2015, 46(1): 143-150.
[14] 陈玉辉, 盛爱珍, 龚涛, 等. 高龄老年非瓣膜性心房颤动合并急性缺血性卒中患者临床特点分析[J]. 中华老年医学杂志, 2018, 37(4): 394-397.
[15] 李海霞, 孟范文, 崔荣太, 等. 高龄老年轻型缺血性卒中患者临床特点和中期预后分析[J]. 中华老年医学杂志, 2019, 38(8): 852-855.