High risk factors and prediction model construction of cardiopulmonary complications in patients with abnormal lung function after pulmonary resection

doi:10.3969/j.issn.1006-7795.2023.06.026

Abstract

Abstract: Objective To investigate the high risk factors and construct prediction model of cardiopulmonary complications in patients with abnormal lung function after pulmonary resection to provide more reference for follow-up clinical diagnosis and treatment. Methods A total of 375 patients with abnormal pulmonary function who underwent pneumonectomy in our hospital from January 2015 to June 2022 were retrospectively enrolled. They were divided into complication group (70 cases) and non complication group (305 cases) according to whether cardiopulmonary complications occurred after surgery. The baseline clinical characteristics of the two groups were compared, and the independent risk factors of cardiopulmonary complications after pneumonectomy were evaluated by Logistic regression model. The predictive model for cardiopulmonary complications after pneumonectomy was developed and predictive efficacy was analyzed. Results Cardiopulmonary complications occurred in 70 of the 375 patients (18.67%). There were significant differences in the the first second forced expiratory volume as a percentage of the predicted value (FEV1%pred), diffusing capacity of the lungs for carbon monoxide as a percentage of the predicted value(DLCO%pred), landing height, heart rate difference before and after stair climb test (SCT), and arterial oxygen saturation difference before and after SCT between the two groups (P<0.05). The results of multi-factor analysis showed that the height of boarding, the difference of heart rate before and after SCT, and the difference of arterial oxygen saturation before and after SCT were independent risk factors for the occurrence of cardiopulmonary complications after pulmonary resection (P<0.05). The Logistic prediction probability was used to predict the occurrence of cardiopulmonary complications after pneumonectomy. The optimal cut-off value was 70.07% and the Jorden index was 54.15%. Conclusion The incidence of cardiopulmonary complications in patients with pulmonary dysfunction after pulmonary resection was closely related to the height of boarding, the difference of heart rate before and after SCT, and the difference of arterial oxygen saturation before and after SCT. The model based on the above factors can accurately predict the risk of postoperative cardiopulmonary complications.

Key words: abnormal lung function, pulmonary resection, complications, model

CLC Number:

R655

Guo Junhao, Jin Gang, Zhao Zhi, Nan Fangyuan, Hu Yunsheng, Hu Qu. High risk factors and prediction model construction of cardiopulmonary complications in patients with abnormal lung function after pulmonary resection[J]. Journal of Capital Medical University, 2023, 44(6): 1081-1086.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2023.06.026

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2023/V44/I6/1081

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