Abstract:

Wistar newborn rats were injected subcutaneously with 10% monosodium glutamate(MSG). The development of rat testes were observed on the 52th(puberty)and 100th day(adult). The results showed that testes weights of MSG group were decreased significantly as compared with control group(P<0.01)in both puberty and adult. MSG treated rats had significantly lower serum concentrations of testosterone than saline treated rats(P<0.01)on both ages. Testes developed arrestedly in MSG group. Spermatogenic cells were consisted of spermatogonia and spermatocyte, spermatid and spermatozoa were not seen in convoluted seminiferous tubule. Thus, MSG can block the spertogenesis.

Key words: monosodium glutamate(MSG), testis, spertogenesis, testosterone