Abstract: One thousand patients, divided randomly into A (epidural ice hypertonic saline 10 mL) and B (ice hypertonic saline 10 mLand fentanyl 0.05 mg) groups. The effect and lasting time were observed. There existed great difference between the two groups in analgesic effect (P<0.01) and no difference in analgesic lasting time (P>0.05). Epidural ice hypertonic saline can attenuate postoperative pain, has a longlasting analgesic effect, reduce the use of postoperative opioid drugs and has no side effects. The effect of saline injection combined with small dose of fentanyl(0.05 mg) is even better without any side effect.

Key words: ice hypertonic saline, postoperative, analgesia