Journal of Capital Medical University ›› 2001, Vol. 22 ›› Issue (4): 292-295.

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Effect of Chinese Herb on c-Jun Expression in Dorsal Root Ganglia in Rats with Spinal Cord Hemisection

Gao Xiulai1, Jing Peng1, Hao Yanli1, Ma Yuping1, Chen Yaliang1, Lu Tao1, Han Fengyue2, Su Jing2, Liu Weidong2, Zhang Ping2, Chang Chaoying2, Liu En2   

  1. 1. Department of Anatomy, Capital University of Medical Sciences;2. Institute of Orthopaedics and Traumatology, China Acad
  • Received:2001-06-29 Revised:1900-01-01 Online:2001-10-15 Published:2001-10-15

Abstract: The object was to study the mechanism of promoting spinal cord regeneration and repair in rats with SCI after spinal cord injury by fluorescence immunohistochemical method combined with laser scanning confocal microscopy. The results indicated that the up-regulation of c-Jun was heightened in dorsal root ganglia of the injury side by the administration of SCI and the number of nerve cells with intact nuclear in SCI administration group was higher. This study showed that SCI could regulate c-Jun expression and promote regeneration of the spinal cord.

Key words: Chinese herb, spinal cord, regeneration, dorsal root ganglia, c-Jun expression

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