Abstract: The objective was to study anoxic brain damage of severe SARS and to investigate the effect of the oxygen therapy.All the 149 patients suffered from severe SARS were treated in Xuanwu Hospital from May 2003 to June 2003.The degree of Anoxic brain damage of84cases with severe hypoxemia were evaluated retrospectively.Result:54cases(64.3%)presented the manifestation of Anoxic brain damage.Among them bradypraxia and less verbal communication were the most common syndrome(92.6%),others included emotional disorder(46.3%),depression or anxiety(40.7%),conscious disturbance(22.2%),cognitive dysfunction(9.3%)and convulsion(1.9%).Through adjusting the model of oxygen supply,the Anoxic syndrome could be improved in a relatively short period(average5d).The patients'breath rate and heart rate decreased,SpO₂ increased and the Anoxic syndrome disappeared.Anoxic brain damage is a significant syndrome and should not be neglected,furthermore correct and reasonable oxygen therapy can increase the curability and decrease the mortality rate of SASR patient.

Key words: SARS, anoxic brain damage, oxygen therapy, prognosis