Emphasis on the Study of Non-Malignant Diseases Associated with EpsteinBarr Virus Infection in Children

Journal of Capital Medical University ›› 2010, Vol. 31 ›› Issue (2): 213-216.

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Emphasis on the Study of Non-Malignant Diseases Associated with EpsteinBarr Virus Infection in Children

XIE Zheng-de, SHEN Kun-ling^*

Laboratory of Virology, Beijing Pediatric Research Institute, Beijing Children's Hospital, Captial Medical University

Received:1900-01-01 Revised:1900-01-01 Online:2010-04-21 Published:2010-04-21
Contact: SHEN Kun-ling

Abstract

Abstract: Epstain-Barr virus(EBV) is an important tumor-related virus, infects over 90% of the world's adult population. EBV is also associated with a wide variety of malignancies including nasopharyngeal carcinoma(NPC), Hodgkin and nonHodgkin lymphomas, gastric carcinoma, posttransplant lymphoproliferative disorder(PTLD). This review introduced laboratory diagnostic assays of EBV infection, and focused on clinical feature and diagnostic guidline of non-malignant diseases associated with EBV infection in children(including infectious mononucleosis, chronic active Epstein-Barr virus infection, EpsteinBarr virus-related hemophagocytic lymphohistiocytosis syndrome). Fields of these diseases needed further research were also introduced.

Key words: EpstainBarr virus, infectious mononucleosis, chronic active EpsteinBarr virus infection, EpsteinBarr virusrelated hemophagocytic lymphohistiocytosis syndrome, children

CLC Number:

R 725.1

XIE Zheng-de;SHEN Kun-ling. Emphasis on the Study of Non-Malignant Diseases Associated with EpsteinBarr Virus Infection in Children[J]. Journal of Capital Medical University, 2010, 31(2): 213-216.

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Emphasis on the Study of Non-Malignant Diseases Associated with EpsteinBarr Virus Infection in Children

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