Journal of Capital Medical University ›› 2010, Vol. 31 ›› Issue (2): 280-281.

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Therapeutic Effect of Low-dose Recombinant Tissue-type Plasminogen Activator on Acute Myocardial Infarction

DING Shun-jin1, LI Yan2   

  1. 1. Department of Cardiovascular Internal Medicine, Beijing Tiantan Hospital, Capital Medical University;2. Department of Cardiovascular, Tangshan Worker’s Hospital, Hebei Medical University
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-04-21 Published:2010-04-21

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Abstract:

Objective To evaluate the therapeutic effect of recombinant tissuetype plasminogen activator(rTPA) on acute myocardial infarction. Methods 72 cases with acute myocardial infarction were treated by lowdose rTPA(50 mg) through 90 min vein injection, the clinic values of blood vessels recanalization, side effects and mortality were observed. Results Reperfusion rate of infarct related vessels was 75%, sixweek mortality was 4.17%, bleeding rate was 14.17%. Conclusion It is safe and efficient of low-dose rTPA on acute myocardial infarction.

Key words: acute myocardial infarction, recombinant tissue plasminogen activator, thrombolytic therapy

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