Journal of Capital Medical University ›› 2020, Vol. 41 ›› Issue (6): 896-900.doi: 10.3969/j.issn.1006-7795.2020.06.006

• Basic and Clinical Research on Plastic Surgery • Previous Articles     Next Articles

The complex landscape of dermal white adipose tissue on skin physiology and pathology

Li Peilin1, Cui lei1,2*   

  1. 1. Department of Plastic Surgery, Beijing Shijitan Hospital,Capital Medical University, Beijing 100038, China;
    2. Department of Central Laboratory, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
  • Received:2020-08-20 Online:2020-12-21 Published:2021-01-18
  • Contact: * E-mail: cuilei8890@bjsjth.cn.
  • Supported by:
    National Natural Science Foundation of China(81471798); Enhancement Funding of Laboratory of Center, Beijing Shijitan Hospital, Capital Medical University(2019-JS04).

Abstract: The dermal white adipose tissue(dWAT)is defined as adipose tissue underlying the reticular dermis,which could modulates skin homeostasis. The studies on the mechanism have revealed that dermal adipose tissue played an essential role in maintenance of hair cycles, healing of cutaneous wounds, and antibacterial ability of innate immune and skin aging. These studies update and deepen our understanding of the complicated interaction between dWAT and skin. It opened a novel avenue to find new targets in the treatment of skin diseases and the intervention of skin aging. This paper reviewed the recent research on dWAT.

Key words: dermal white adipose tissue, hair follicle, wound healing, innate immune, skin aging

CLC Number: