Journal of Capital Medical University ›› 2021, Vol. 42 ›› Issue (6): 1076-1080.doi: 10.3969/j.issn.1006-7795.2021.06.029

• Clinical Research • Previous Articles     Next Articles

Clinical value of torasemide combined with 50% glucose rapid diuretic ultrasonography in the diagnosis of renal microcalculi in pilot service

Kang Li1, Li Shuo1, Xiong Ying2*, Guo Ruijun1*   

  1. 1. Department of Ultrasound Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China;
    2. Department of Ultrasound Medicine, Civil Aviation General Hospital, Beijing 100123, China
  • Received:2021-04-15 Online:2021-12-21 Published:2021-12-17
  • Contact: * E-mail: xy19720630@163.com, ruijunguo@126.com

Abstract: Objective To investigate the clinical value of tolasemide combined with 50% glucose rapid diuretic ultrasound test in the diagnosis of renal microcalculi in flight crew. Methods A total of 189 flight crew in service suspected of renal microcalculi and renal calcification by conventional ultrasonography were examined by tolasemide combined with 50% glucose rapid diuretic ultrasonography. Comparing the results of flexible ureteroscopy as the gold standard, to evaluate the accuracy of diuretic ultrasonography in renal microcalculus. Results Among 189 pilots, 160 cases of renal microcalculi were diagnosed by conventional ultrasound (176 calculi), 10 cases of calcification (20 calcification foci), 19 cases of undefinable diagnosis (19 strong echo points). 155 cases of renal microcalculi (307 calculi) and 34 cases of calcification (45 calcification foci) were diagnosed after diuretic ultrasonography. All the patients diagnosed with renal microcalculi underwent medical lithotripsy or laser lithotripsy. Half a year later, 90 calculi in 20 cases disappeared, and the remaining 169 flight crew were admitted to the hospital for flexible ureteroscopic surgery. 210 calculi in 139 cases and 52 calcification foci in 30 cases were found. There was a statistical difference between conventional ultrasound and post-diuretic ultrasound examination in the diagnosis of renal microcalculi (P<0.001); there was a statistical difference between conventional ultrasound and flexible ureteroscopy in the diagnosis of renal microcalculi (P=0.026), the sensitivity and specificity of conventional ultrasonography in the diagnosis of renal microcalculi were 58.7% and 75.0%. There was no statistically significant difference between post-diuretic ultrasound examination and flexible ureteroscope examination of renal microcalculi (P=0.874), the sensitivity and specificity of post-diuretic ultrasound in the diagnosis of renal microcalculi were 97.7% and 86.5%. Conclusion Torasemide combined with 50% glucose rapid post-diuretic ultrasound can significantly improve the diagnostic efficiency of renal microcalculi, and it can be used as the preferred method for early diagnosis and treatment of renal microcalculi in flight service.

Key words: microcalculi, diuresis test, ultrasound, flexible ureteroscope

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