Journal of Capital Medical University ›› 2001, Vol. 22 ›› Issue (2): 129-131.

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Effect of Bisoprolol on Heart Function in Old Myocardial Infarction

Yu Dongming, Li Qun, Wang Jie, Wang Jiong, Li Jihong, Zhang Huadong   

  1. Department of Cardiovascular Disease, Beijing Tiantan Hospital, Affilate of Capital University of Medical Sciences
  • Received:2000-07-18 Revised:1900-01-01 Online:2001-04-15 Published:2001-04-15

Abstract: To investigate the effects of bisoprolol on heart function in old myocardial infarction(OMI), 35 patients with OMI received bisoprolol 2.5 mg per day for two months. Doppler echocardiographic measurements of left ventricular structure, transmitral flow velocity pattern, blood pressure and heart rate were monitored before and after 1 and 2 months therapy. Bisoprolol led to reduction in blood pressure and heart rate 〔(20.08/10.64±3.33/2.26)vs(19.42/10.37±2.79/1.86)kPa P<0.01,(70.66±12.86)vs(64.31±9.84)bits/min P<0.01〕, and E/A increased significantly 〔(0.85±0.18)vs(1.14±0.35)P<0.01〕. No significant affection was found on left ventracular systolic function. Bisoprolol reduces blood pressure and heart rate, improves diastolic function, hence it would be valuable in treatment of OMI.

Key words: myocardial infarction, diastolic function, echocardiography

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