Correlation of white blood cell count and prognosis in patients with acute non-ST-segment elevation myocardial infarction

doi:10.3969/j.issn.1006-7795.2016.04.027

Abstract

Abstract: Objective We aimed to evaluate the relationship between white blood cell count(WBC) and prognosis in patients with non-ST-segment elevation myocardial infarction(NSTEMI).Methods We retrospectively enrolled 198 patients with NSTEMI and analyzed follow-up data. All patients were admitted to hospital after immediate detection of WBC. Mortality, re-infarction, revascularization, and stroke were the primary end point.Multivariate regression revealed prognostic factors. Results There was no significant difference of the baseline data except of heart rate and creatine kinase isozyme between two groups.We found that patients of WBC>11.0×10⁹/L group had more main adverse cardiovascular and cerebrovascular events(MACCE) at the time in hospital and in the six months after discharge than those of WBC≤11.0×10⁹/L group.In multivariate logistic regression analysis, WBC>11.0×10⁹/L (OR=2.942, 95%CI: 1.333-6.495, P=0.008) was independent predictors for MACCE at the time in hospital. In multivariate cox regression analysis, WBC>11.0×10⁹/L (RR=3.767, 95%CI:1.406-10.089, P=0.008) was independent predictors for MACCE in the six months after discharge.There was no significant differences of the baseline data except of heart rate and creatine kinase isozyme between two groups.We found that patients of WBC>11.0×10⁹/L group had more main adverse cardiovascular and cerebrovascular events(MACCE) at the time in hospital and in the six months after discharge than those of WBC≤11.0×10⁹/L group.In multivariate Logistic regression analysis, WBC>11.0×10⁹/L (OR:2.942, 95%CI:1.333-6.495, P=0.008) was independent predictors for MACCE at the time in hospital. In multivariate cox regression analysis, WBC>11.0×10⁹/L (RR:3.767, 95%CI:1.406-10.089, P=0.008) was independent predictors for MACCE in the six months after discharge. Conclusion The high WBC is an independent predictor of MACCE in patients with NSTEMI.

Key words: white blood cell count, non-ST-segment elevation myocardial infarction, prognosis

CLC Number:

Li Qun, Wang Dezhao, Wang Jun, Hu Hongyu, Fu Qiang, Chen Wei, Guo Caixia, Chen Buxing. Correlation of white blood cell count and prognosis in patients with acute non-ST-segment elevation myocardial infarction[J]. Journal of Capital Medical University, 2016, 37(4): 550-554.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2016.04.027

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2016/V37/I4/550

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