Use of antibiotics in postoperative intracranial infection patients in neurosurgery

doi:10.3969/j.issn.1006-7795.2013.02.003

Abstract

Abstract:

Objective To understand the situation of antibiotics use and intracranial infections in postoperative patients in neurosurgical department. Methods The data of the time of intracranial infection, bacteria detected in cerebrospinal fluid(CSF) culture and the use of the antibiotics were collected in patients who underwent neurosurgery from January 2009 to June 2011. Results Among 21 067 cases, positive results of CSF culture accounted for 1.2%(253 cases). The mean time from operation to intracranial infection occurrence was 7.2 days, the time to obtain culture result was 10.2 days. The most frequently isolated bacterium was coagulase negative staphylococcus(28.85%), followed by Staphylococcus aureus(14.62%). Antibiotics were empirically used in all CSF positive patients. Antibiotics were sensitive in 33.4% of empiric use cases and 82.9% of the cases in whom antibiotics were used against specific targets were sensitive. Conclusion The positive rate of CSF culture was low. The coagulase negative staphylococci and Staphylococcus aureus play important role in intracranial infection. Though antibiotics are used often, adequate use should be emphasized.

Key words: postoperative intracranial infection, neurosurgery, antibiotics

CLC Number:

R651.1⁺1

YUE Xiaoyan, SHI Guangzhi. Use of antibiotics in postoperative intracranial infection patients in neurosurgery[J]. Journal of Capital Medical University, 2013, 34(2): 177-180.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2013.02.003

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2013/V34/I2/177

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