A retrospective analysis of post-craniotomy intracranial infection in pediatric patients with supratentorial neurosurgical operation: incidence, risk factors and outcome

doi:10.3969/j.issn.1006-7795.2015.03.023

Abstract

Abstract:

Objective To investigate the incidence, risk factors and outcomes of post-craniotomy intracranial infection (PCII) in pediatric patients with supratentorial neurosurgical operation in our hospital.Methods Pediatric patients who were undergone supratentorial neurosurgical operation in our hospital from 2011 to 2012 were included. The medical records, imaging findings, and laboratory were reviewed for investigating the incidence, risk factors, and outcomes of patients had PCII. Results The incidence of PCII was 8.0%. Postoperative drainage tube placement, and postoperative head CT showing intracranial hemorrhage were independent risk factors for PCII (odds ratio <1, P >0.05). Administration of prophylactic antibiotics did not reduce the incidence of PCII.Conclusion The overall incidence of PCII was 8.0%. Patients with PCII had longer hospital stay and higher hospital cost, indicating that patients with PCII should be carefully managed.

Key words: pediatric neurosurgical patients, supratentorial neurosurgical operation, intracranial infection, prophylactic antibiotics, risk factors

CLC Number:

R651

Xu Ming, Shi Zhonghua, Chen Guangqiang, Zhao Jingwei, Shi Guangzhi, Wang Tao, Wang Xin, Tang Mingzhong, Zhou Jianxin. A retrospective analysis of post-craniotomy intracranial infection in pediatric patients with supratentorial neurosurgical operation: incidence, risk factors and outcome[J]. Journal of Capital Medical University, 2015, 36(3): 454-458.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2015.03.023

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2015/V36/I3/454

References

[1] Patir R, Mahapatra A K, Banerji A K. Risk factors in postoperative neurosurgical infection: a prospective study[J]. Acta Neurochir,1992,119(1-4):80-84.
[2] Korinek A M, Baugnon T, Golmard J L, et al. Risk factors for adult nosocomial meningitis after craniotomy: role of antibiotic prophylaxis[J]. Neurosurgery,2006,59(1):12-33.
[3] 张国锋,胡卫星,顾培元,等. 脑干桥延部肿瘤显微外科手术治疗及并发症的防治[J].中华神经外科杂志,2013,29(4):367-369.
[4] 张震军,张春阳,苏里,等.颅脑术后或创伤后颅内感染的治疗体会[J].中华神经外科杂志,2012,28(8):809.
[5] Porras-Hernández J D, Vilar-Compte D, Cashat-Cruz M, et al. A prospective study of surgical site infections in a pediatric hospital in Mexico City[J].Am J Infect Control,2003,31(5):302-308.
[6] Buckwold F J, Hand R, Hansebout R R. Hospital-acquired bacterial meningitis in neurosurgical patients[J].J Neurosurg,1977,46(4):494-500.
[7] Yang Z J, Zhong H L, Wang Z M, et al. Prevention of postoperative intracranial infection in patients with cerebrospinal fluid rhinorrhea[J]. Chin Med J:Engl, 2011,124(24):4189-4192.
[8] Mangram A J, Horan T C, Pearson M L, et al. Guideline for prevention of surgical site infection,1999. Hospital Infection Control Practices Advisory Commitlee[J]. Infect Control Hosp Epidemiol,1999,20(4):247-278.
[9] Daabiss M. American Society of Anaesthesiologists physical status classification[J]. Indian J Anaesth, 2011, 55(2):111-115.
[10] Miller P R, Johnson J C, 3rd, Karchmer T, et al. National nosocomial infection surveillance system: from benchmark to bedside in trauma patients[J]. J Trauma,2006, 60(1): 98-103.
[11] van de Beek D, Drake J M, Tunkel A R. Nosocomial bacterial meningitis[J]. N Engl J Med,2010,362(2):146-154.
[12] McClelland S 3rd, Hall W A. Postoperative central nervous system infection: incidence and associated factors in 2111 neurosurgical procedures[J]. Clin Infect Dis,2007,45(1):55-59.
[13] 史占华,赵鸿玲.神经外科重症监护病房医院感染分析[J]. 中国煤炭工业医学杂志,2012,15(5):713-714.
[14] 魏俊吉,康德智,赵元立,等.神经外科重症管理专家共识(2013版)[J]. 中国脑血管病杂志,2013,10(8):436-448.
[15] 岳晓艳,石广志.神经外科术后颅内感染患者的抗生素使用[J]. 首都医科大学学报,2013,34(2):177-180.