Research progress in the pathogenesis of Alzheimer's disease

doi:10.3969/j.issn.1006-7795.2014.06.009

Abstract

Abstract:

Alzheimer's disease (AD), also known as senile dementia, is a degenerative disease of the nervous system. It is the most common type of dementia, and its incidence in the elderly is increasing all the time, the major clinical manifestations of AD are progressive memory loss, cognitive dysfunction, and other neuropsychiatric symptoms and behavioral disorders. The etiology of Alzheimer's disease is not yet clear, and its pathogenesis is complex, this article reviews briefly the past and recent important findings of potential relevance to the pathogenesis of Alzheimer's disease.

Key words: Alzheimer's disease, pathogenesis, amyloid, insulin signaling pathway

CLC Number:

R741

Zhang Jingshuang, Wang Rong. Research progress in the pathogenesis of Alzheimer's disease[J]. Journal of Capital Medical University, 2014, 35(6): 721-724.

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