Abstract: Objective To investigate the risk factors of deep venous thrombosis (DVT) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods A total of 51 patients with AECOPD admitted to the emergency ward of our hospital from October 2018 to April 2019 were collected and divided into the thrombotic group and the non-thrombotic group according to the results of lower extremity vein color Doppler ultrasound report after admission, and the basic data, clinical characteristics and examination results of the two groups were compared. Results In the presence of lower extremity edema, pulmonary hypertension, average pressure, D-dimer of significant differences between the two groups of patients (P< 0.05), the results of single factor analysis of meaningful factors multivariable Logistic regression analysis, the results show lower extremity edema and pulmonary hypertension are AECOPD combined independent risk factors for DVT (P<0.05, OR=5.215, 3.741), but mean arterial pressure and D-dimer are not AECOPD combined independent risk factors for DVT (P>0.05).There was no significant difference in C-reactive protein, interleukin-6, interleukin-8, tumor necrosis factor, and arterial partial oxygen pressure between the two groups (P>0.05). Conclusion For AECOPD patients, the possibility of deep venous thrombosis can be inferred from the lower limb edema, pulmonary hypertension, and then the diagnosis and prevention of lower limb deep vein thrombosis can be achieved through targeted examination and treatment.

Key words: acute exacerbation of chronic obstructive pulmonary disease, deep venous thrombosis, clinical characteristics, risk factors