Correlation between serum vitamin D level and thyroid function and clinical characteristics in the newly-diagnosed type 2 diabetes mellitus patients

doi:10.3969/j.issn.1006-7795.2017.02.005

Abstract

Abstract: Objective To observe relation between serum vitamin D level and thyroid function, clinical characteristics in the newly-diagnosed type 2 diabetes mellitus(T2DM) patients.Methods A total of 239 patients with the newly-diagnosed T2DM were selected in Department of Endocrinology, Beijing Chuiyangliu Hospital from May 2015 to October 2016. According to serum 25-hydroxyvitamin D[25(OH)D] level, these patients were divided into four groups:normal group ≥30 ng/mL, insufficiency group 20 ng/mL≤25(OH)D<30 ng/mL, deficiency group 10 ng/mL≤25(OH)D<20 ng/mL and severe deficiency group<10 ng/mL. Clinical characteristics and thyroid function were compared in these groups.Results The incidence of serum 25(OH)D deficiency was 56.9% in the newly-diagnosed T2DM group.There were significant differences in age, glycosylated hemoglobin (HbA1c), thyroid stimulating hormone (TSH) in these groups (P<0.05).The linear regression analysis showed that serum calcium (Ca), parathyroid hormone (PTH) were positively correlated with serum 25(OH)D (P<0.05), but gender, age, smoking, HbA1c, TSH were negatively correlated with serum 25(OH)D (P<0.05).Conclusion Female, age, smoke, HbA1c, TSH are important risk factors for deficiency of serum 25(OH)D in the newly-diagnosed T2DM patients.

Key words: type 2 diabetes mellitus, vitamin D, thyroid function, thyroid stimulating hormone

CLC Number:

Cui Limei, Liu Cuiping, Fu Hanjing, Yan Yehua, Zheng Xiaomin, Tao Jing, Feng Jianping, Yuan Mingxia, Yang Jinkui. Correlation between serum vitamin D level and thyroid function and clinical characteristics in the newly-diagnosed type 2 diabetes mellitus patients[J]. Journal of Capital Medical University, 2017, 38(2): 167-171.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2017.02.005

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2017/V38/I2/167

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