Journal of Capital Medical University ›› 2017, Vol. 38 ›› Issue (6): 795-799.doi: 10.3969/j.issn.1006-7795.2017.06.003

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Results of individual extralevator abdominoperineal resection for locally advanced low rectal cancer

Han Jiagang, Wang Zhenjun, Wei Guanghui, Gao Zhigang, Yang Yong, Zhai Zhiwei, Zhao Baocheng   

  1. Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China
  • Received:2017-10-16 Online:2017-11-21 Published:2017-12-16
  • Supported by:
    This study was supported by National High Technology Research and Development Program of china (2015AA033602), National Natural Science Foundation of China (81541101), Capital Characteristic Clinic Project of Beijing (Z121107001012131), New Century Talents Project (09-911-002), The Capital Health Research and Development of Special (2009-3109, 2014-4-2033), Project of Beijing Chaoyang Hospital 1351 talents training, the Basic and Clinical Cooperation Project of Capital Medical University (15JL03).

Abstract: Objective To evaluate the safety and efficacy of individualized extralevator abdominoperineal excision (ELAPE) for locally advanced low rectal cancer.Methods Fifty-six patients who underwent individualized abdominoperineal resection (APR) based on magnetic resonance imaging (MRI) from June 2011 to June 2015 were evaluated. The main outcome measures were circumferential resection margin involvement, intraoperative perforation, postoperative complications, and local recurrence. Results During the study, fifty patients (89.3%) received preoperative chemoradiotherapy.The common complications included perineal wound infection (9/56, 16.1%), sexual dysfunction (5/41, 12.2%), urinary retention (4/56, 7.1%) and chronic perineal pain (3/56, 5.4%). A positive circumferential resection margin (CRM) was demonstrated in 3 (5.4%) patients, and intraoperative perforations occurred in 2 (3.6%) patient. The local recurrence was 3.6% at a median follow-up of 35 months (range, 12-60 months).Conclusion With adequate preoperative chemoradiotherapy and MRI precise guideline, individualized ELAPE might be a relatively safe and feasible approach for locally advanced low rectal cancer with acceptable oncological outcomes.

Key words: rectal cancer, individualized, extralevator abdominoperineal excision, complications, local recurrence

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