Journal of Capital Medical University ›› 2018, Vol. 39 ›› Issue (1): 6-8.doi: 10.3969/j.issn.1006-7795.2018.01.002

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Epidemiology of sepsis in China

Du Bin, Weng Li   

  1. China Critical Care Clinical Trials Group, Medical Intensive Care Unit, Peking Union Medical College Hospital, Beijing 100730, China
  • Received:2017-11-13 Online:2018-01-21 Published:2018-01-27
  • Supported by:
    This study was supported by Capital Clinical Application Research Grant (Z1311017002213112), Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (CIFMS) (2016-I2M-1-014).

Abstract: As the leading cause of death in intensive care unit (ICU) patients, epidemiology of sepsis remains poorly understood until the recent years.The prevalence of severe sepsis was reported as 8.7% in critically ill patients in surgical ICUs, and 37.3% in general ICUs, with the latter similar to the average prevalence of sepsis in European ICUs. However, ICU-based prevalence of sepsis was prone to underestimation, as up to 86% of septic patients might be managed in general wards rather than in ICU. Population-based epidemiology of sepsis was studied in only one cohort study of all hospitalized adults in a subdistrict of Beijing, which reported the standardized incidence of sepsis as 461 cases per 100 000 population, corresponding to 4.86 million cases per year in China. In addition, based on National Mortality Surveillance System, the preliminary data from an ongoing study showed that 14.5% of all deaths was attributable to infection, corresponding to standardized mortality of 76.8 deaths per 100 000 population, or more than 1 million deaths in 2015. Moreover, data on long-term outcomes were available for only 33 sepsis survivors, which suggested lower quality of life during a follow-up of up to 6 years. The above data suggested that the disease burden of sepsis was high in China, which was important for the design of relevant health care policies, allocation of limited health resources, and development of prevention measurements.

Key words: sepsis, epidemiology, incidence, prevalence, fatality

CLC Number: